Subtypes of the Gc gene (vitamin D binding protein) in the Polish population |
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| Authors: | D Le?ko D Schlesinger J Ha?asa M Mańczak |
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| Institution: | Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroc?aw. |
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| Abstract: | Gc subtypes were analyzed by isoelectric focusing on thin-layer polyacrylamide gel. In the sample of the Polish population including 278 persons, six Gc phenotypes were encountered: 1S, 1F-1S, 1F, 2-1S, 2-1F, 2 with the following frequencies: 0.342, 0.151, 0.014, 0.360, 0.072 and 0.061. Frequency of Gc1S was 0.597, Gc1F - 0.126 and Gc2 - 0.277. It was shown that a group system of the Gc protein in the Polish population was in good agreement with Hardy Weinberg equilibrium. |
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