Storage of Platelet Concentrates at 22{degrees}C |
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| Authors: | MURPHY, SCOTT SAYAR, SEYED N. GARDNER, FRANK H. |
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| Affiliation: | 1 Research Hematology Laboratory, Presbyterian University of PennsylvaniaMedical Center, and the Department of Medicine, University of Pennsylvania School ofMedicine, Philadelphia, Pa.
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| Abstract: | A technique has been proposed which allows easy preparation of plateletconcentrates within a closed, sterile system and maximal utilization of otherblood components. Lifespan studies have been performed to demonstrate theviability of platelets prepared in this manner. Such concentrates can be storedfor as long as three days with adequate maintenance of viability for tranfusionpurposes if certain technical requirements are met. Important among theseare attention to concentrate volume and pH; agitation of the concentrate ishelpful for maintenance of viability. Twelve studies in thrombocytopenic recipients suggest that stored concentrates will be safe and effective in transfusionpractice. Submitted on September 27, 1969 Accepted on January 2, 1970 |
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