| 胎盘生长因子在冠心病领域的研究进展 |
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| 引用本文： | 李永斌,吕树铮. 胎盘生长因子在冠心病领域的研究进展[J]. 心血管病学进展, 2007, 28(6): 934-936 |
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| 作者姓名： | 李永斌 吕树铮 |
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| 作者单位： | 首都医科大学附属北京安贞医院心内科,北京,100029 |
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| 摘 要： | 胎盘生长因子(PlGF)是血管内皮生长因子(VEGF)家族成员之一,最近的研究表明PlGF同粥样硬化斑块的进展相关,代表斑块的不稳定性;PlGF水平同急性冠脉综合征患者的预后相关,可以作为预后的独立预测因子;此外,急性心肌梗死后PlGF水平升高,并且同恢复期左室功能改善程度相关。
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| 关 键 词： | 胎盘生长因子 动脉粥样硬化 急性冠脉综合征 |
| 文章编号： | 1004-3934（2007）06-0934-03 |
| 修稿时间： | 2007-01-23 |
Progress in Clinical Research into Placental Growth Factor in Coronary Artery Disease |
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| LI Yong-bin,LU Shu-zheng. Progress in Clinical Research into Placental Growth Factor in Coronary Artery Disease[J]. Advances in Cardiovascular Diseases, 2007, 28(6): 934-936 |
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| Authors: | LI Yong-bin LU Shu-zheng |
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| Affiliation: | Department of Cardiology,Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing 100029, China |
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| Abstract: | Placental growth factor (PlGF) is a member of the VEGF family. Recent research has shown the relationship between PlGF and the progression of atherosclerosis plaque, indicating that PlGF may represent the instability of plaque. Clinical research has shown that serum PlGF level is an independent biomarker of adverse outcome in patients with chest pain and acute coronary syndrome patients. In addition, the level of PlGF increases in AMI patients and then acts to improve LVEF during the chronic phase. |
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| Keywords: | placental growth factor atherosclerosis acute coronary syndrome |
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