班氏丝虫病基本消灭后残存微丝蚴血症者传播丝虫病作用的研究

在班氏丝虫病基本消灭后地区,人群微丝蚴与微丝蚴密度已无相关关系。淡色库蚊叮咬微丝蚴密度为120立方毫米血内一条的患者,仍能获得感染;叮咬微丝蚴密度为120立方毫米血内2条的患者时,蚊虫的最高感染度可达5条感染期幼虫。在微丝蚴率为0.56%的试验村内进行调查,采用I期、Ⅱ期幼虫发育至感染期幼虫的时间内淡色库蚊的存活概率作为校正值参与丝虫病季传播潜势的估算,结果为试验村内平均每人每季可受到淡色库蚊的12,384次叮咬,12次为感染叮咬,可接种34条感染期幼虫。

Studies on the Role of Residual Miorofilaraemia in Bancroftian Filariasis Transmission in Controlled Area

There was no relationship between microfilarial rate and microfilarial density after Bancroftian filariasis was basically eradicated. C. pipiens pallens could intake microfilariae from a patient with 1 microfilaria in 120mm³ blood, the highest infected density reached 5 infective larvae in the mosquitoes which sucked blood of carrier with 2 microfilariae in 120mm³ blood. An observation was carried out in a village with microfilarial rate of 0.56%. We used all stages of larvae and took probability of mosquito survival time in which first or second stage larvae can develop to the third stage as a corrector to estimate seasonal transmission potential of Bancroftian filariasis, the result showed that every villager would have been bitten by 12,348 mosquitoes, including 12 infective bites, and inoculated 34 infective larvae in whole season.