| 正交设计优选健脾颗粒中橙皮苷的提取工艺 |
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| 引用本文： | 林清,符小英,马晓鹂. 正交设计优选健脾颗粒中橙皮苷的提取工艺[J]. 中国医院用药评价与分析, 2013, 0(5): 446-448 |
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| 作者姓名： | 林清 符小英 马晓鹂 |
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| 作者单位： | [1]广东医学院附属医院药学部,广东湛江524001 [2]广东恒诚制药有限公司,广东湛江524022 |
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| 摘 要： | 目的：优选健脾颗粒中橙皮苷的提取工艺。方法：以处方中的主要药效成分橙皮苷含量为观察指标,采用正交设计法筛选最佳提取工艺条件。结果：最佳提取方法为回流1.0 h、加95%甲醇50 ml。结论：优选的提取方法为健脾颗粒中橙皮苷含量测定提供可靠方案,保证产品质量。
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| 关 键 词： | 正交设计 橙皮苷 提取工艺 |
Optimization of Extraction Technology of Hesperidin in Jianpi Granules Using Orthogonal Design |
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| LIN Qing,FU Xiao-ying,MA Xiao-li. Optimization of Extraction Technology of Hesperidin in Jianpi Granules Using Orthogonal Design[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2013, 0(5): 446-448 |
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| Authors: | LIN Qing FU Xiao-ying MA Xiao-li |
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| Affiliation: | ( ( 1. Dept. of Pharmacy, The Affiliated Hospital of Guangdong Medical College, Guangdong Zhanjiang 524001, China; 2. Guangdong Hengcheng Pharmaceutical Co. Ltd., Guangdong Zhanjiang 524022, China) |
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| Abstract: | OBJECTIVE：To optimize the extraction technology of hesperidin in Jianpi granules （granules for strengthening spleen）. METHODS： The extraction technology of hesperidin in Jianpi granulea was optimized using orthogonal design with the main active component hesperidin as observation index. RESULTS： The optimal extracting technology for hesperidin were as follows： 95% methanol （50 ml） were added for refluxing of 1 hour. CONCLUSION： The optimized extraction technology serves as a reliable scheme for determination of the content of hesperidin in Jianpi granules and thus ensuring the quality of Jianpi granules. |
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| Keywords: | Orthogonal design Hesperidin Extraction technology |
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