氩激光488nm波长与混合波长光动力治疗鲜红斑痣的比较研究

目的为探索氩激光光动力治疗鲜红斑痣（ＰＷＳ）更为安全的方法，比较了４８８ｎｍ单波长和常用混合波长氩激光的疗效及不良反应。方法随机选择５２例患者分为２组分别采用４８８ｎｍ单波长氩激光及混合波长氩激光进行治疗。结果４８８ｎｍ单波长激光组的治愈率为１９．２３％，混合波长组为１１．５４％，两者无显著差异。总有效率分别为９２．３１％％及８８．４６％，无统计学差异。不良反应的发生率为混合波长组高于单一波长组，

Comparative Research on Mixed and 488nm Argon Laser PDT for Port Wine Stain

Objective In order to search a safer argon laser photodynamic method, this study used 488nm wavelength and common mixed spectrum argon laser PDT for treating Port Wine Stain. The therapeutic effects and side effect were compared.Methods Fifty two cases of PWS were divided into two groups randomly. Argon laser PDT by two ways of laser irradiation were used.Results Our data revealed 19.23% cure rate in 488 nm laser PDT group, while that of mixed wavelength laser group was 11.54%. There was no significant difference in the two groups. Also the effective rate of 488nm laser group was 92.31% and that of mixed group was 88.46%. But the difference was not significant statistically. Side effect occurred often in mixed spectrum laser group. That was 57.69% for mixed group, 38.46% for 488nm group.Conclusion Argon laser PDT at 488nm had the similar therapeutic result contrasted to mixed spectrum laser group, but it was safe.