| 比索洛尔治疗充血性心力衰竭临床观察 |
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| 引用本文： | 宗文霞,林琍.比索洛尔治疗充血性心力衰竭临床观察[J].数理医药学杂志,2011,24(1):88-90. |
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| 作者姓名： | 宗文霞 林琍 |
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| 作者单位： | 湖北省中山医院心内科武汉430033 |
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| 摘 要： | 目的:观察比索洛尔治疗充血性心力衰竭疗效。方法:54例充血性心力衰竭患者,在常规治疗病情基本稳定的基础上,随机分为对照组25例和治疗组29例。对照组给予地高辛、利尿剂、血管紧张素转换酶抑制剂(ACEI)或血管紧张素受体拮抗剂(ARB)治疗;治疗组在常规治疗的基础上,给予比索洛尔治疗,比索洛尔从1.25 mg Qd开始,缓慢递增,至10 mg Qd或最大耐受剂量,随访时间为12周。治疗前后分别进行心功能(NYHA)分级、血压、心率测定、超声心动图检查并做统计学处理。结果:与治疗前相比:对照组心功能分级改善(P<0.05),左室射血分数(LVEF)增加(P<0.05);治疗组心功能分级显著改善(P<0.01),LVEF和左室短轴缩短率(FS)明显增加(P<0.01),左室舒张末期内径(LVDd)显著缩短(P<0.01),左室收缩末期内径(LVDs)缩短(P<0.05)。两组治疗后相比,比索洛尔组LVEF、FS较常规组改善更为显著(P<0.01)。结论:比索洛尔在心衰常规治疗基础上治疗充血性心力衰竭有良好的疗效,能显著改善心功能,改善衰竭左室的重构。
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| 关 键 词： | 比索洛尔 充血性心力衰竭 心功能 β-受体阻滞剂 |
Effect of Bisoprolol in Treatment of Chronic Heart Failure |
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| Zong Wenxia,et al.Effect of Bisoprolol in Treatment of Chronic Heart Failure[J].Journal of Mathematical Medicine,2011,24(1):88-90. |
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| Authors: | Zong Wenxia |
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| Institution: | Zong Wenxia,et al(Department of Cardiology,Hubei Zhongshan Hospital,Wuhan 430033) |
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| Abstract: | Objective:To evaluate the efficacy of bisoprolol in chronic heart failure.Methods: 54 patients of dilated cardiomypathy with chronic heart failure were enrolled in the study,among whom 25 were assigned to treatment group and 29 to control group.Before enrollment,all patients received routine drugs such as: digitalis,diuretics,ACEI or ARB.In the control group,the subjects were maintained routine drugs,while those in the treatment group given bisoprolol in addition to the routine drugs.Bisoprolol was added on... |
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| Keywords: | bisoprolol chronic heart failure NYHA class β-Blocker |
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