电针镇痛时突触后膜厚度的变化

<正> 我们过去的工作曾揭示:电针镇痛时,小鼠脑内某些核团的突触后膜有明显的增厚现象。由于化学突触的后膜是神经递质受体所在部位,这种显著的增厚现象引起了我们的重视。为了进一步验证其厚度变化的规律性,我们再一次测定了针刺镇痛所引起的丘脑束旁核,中脑中缝背核和中脑中央灰质等部位突触后膜(包括突触后电子致密物质,并一律测量最宽处)的厚度变化。实验动物仍为正常健康的成年小白鼠,雌雄兼

THE CHANGES IN THE THICKNESS OF POSTSYNAPTIC MEMBRANE DURING ACUPUNCTURE ANALGESIA

The present article reports the results on the evident increase of thickness of the postsynaptic membrane in some nuclei of the mice brain during acupuncture analgesia. The investigated regions of the mice brain are thalamus parafascicularis nucleus, mid-brain dorsal raphe and mid-brain grey matter. The thickness of the postsynaptic membrane in these regions was measured on the electron micrograph by the micrometer of the light microscope. The obtained data show that the differences between acupuncture analgesia group and control group are marked, the former being larger than the latter. It is suggested that the changes in synaptic ultrastructure during the acupuncture analgesia are regarded as a reflection of the unity between structure and function in the central nervous system. Because the postsynaptic membrane is the site of the neurotransmitter's receptors in action, it is possible that the mechanism of synaptic chemical transmission is morphologically reflected in the significant thickening of postsynaptic membrane in some brain regions which take part in the process of acupuncture analgesia.