早产儿呼吸机相关性肺炎59例临床分析

目的探讨早产儿并发呼吸机相关性肺炎(VAP)的临床特点及预防措施。方法对98例机械通气治疗的患儿进行回顾性分析。结果有59例患儿发生VAP,发生率为60.20%;死亡25例,病死率为42.37%。其主要病原菌为革兰阴性杆菌,占81.25%,其中以肺炎克雷伯菌、铜绿假单胞菌、大肠埃希菌为多见。结论死亡原因与严重VAP有直接关系。机械通气时间与VAP发生有关,减少细菌吸入可降低VAP发生率。

Clinical analysis on ventilator-associated pneumonia in premature of 59 cases

Objective To explore the clinical characteristics and preventive measures of ventilator-associated pneumonia(VAP) in premature.Methods Retrospective analysis on the treatment through mechanical ventilating of 98 cases of patients.Results 59 cases were resulted in VAP and its incidence is 60.20%,25 cases were resulted in death,and its mortality is 42.37%.Their main pathogen is gram-negative bacteria which takes 81.25% and most of them are klebsiella pneumonia,pseudomonas aeruginosa,stenotrophomonas maltophilia.Conclusions The cause of death has directive relation with severe VAP.The duration of mechanical ventilating is associated with the VAP and decreasing the bacterial inhalation can reduce the incidence of VAP.