| 氯化锰对小鼠精子生成的影响 |
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| 引用本文： | 李兴升,才秀莲,李季蓉,张先平. 氯化锰对小鼠精子生成的影响[J]. 遵义医学院学报, 2004, 27(3): 222-223 |
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| 作者姓名： | 李兴升 才秀莲 李季蓉 张先平 |
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| 作者单位： | 遵义医学院,组织胚胎学教研室,贵州,遵义,563003 |
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| 摘 要： | 目的研究染锰对小鼠精子生成的影响,并探讨其时间-效应关系和剂量-效应关系.方法将雄性小鼠随机分为3个染锰组和1个对照组,给予各组小鼠腹腔注射7.5、15.0、30.0mg/kg氯化锰和生理盐水,分别于第3、7、14、28、56d各组处死5只小鼠,观察精子计数.结果各染锰组分别于染锰不同时间出现精子数量的降低,且随着染锰剂量的增加和时间的延长而逐渐加重.结论氯化锰可对小鼠精子生成有明显的损害作用,且有一定的时间-效应关系和剂量-效应关系.
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| 关 键 词： | 氯化锰 小鼠 精子生成 |
| 文章编号： | 1000-2715(2004)03-0222-02 |
Effects of manganese chloride exposure on spermatogenesis in mice |
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| LI Xing sheng,CAI Xiu lian,LI Ji rong,ZHANG Xian ping. Effects of manganese chloride exposure on spermatogenesis in mice[J]. Acta Academiae Medicine Zunyi, 2004, 27(3): 222-223 |
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| Authors: | LI Xing sheng CAI Xiu lian LI Ji rong ZHANG Xian ping |
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| Abstract: | Objective To study the effect of manganese chloride exposure on spermatogenesis in mice, and explore the dose effects and time effects. Methods The study mice were divided into 3 treatment groups with manganese chloride (7.5,15.0,30.0mg/kg) and 1 control group with NS. The quantity of sperm was investigated after 5 different time (3,7,14,28,56d) i.p. administration MnCl 2 (7.5,15,30mg/kg). Results Results shows the quantity of sperm were significantly decreased after different time in exposed groups respectively. Conclusions It is suggested that MnCl 2 might damage the spermatogenesis in mice,and there existed dose effects and time effects. |
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| Keywords: | manganese chloride mouse spermatogenesis activity of sperm |
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