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血管周上皮样细胞肿瘤的临床病理学观察
引用本文:张淑红,黄受方,陆鸣,郑媛媛. 血管周上皮样细胞肿瘤的临床病理学观察[J]. 临床和实验医学杂志, 2011, 10(15): 1149-1152
作者姓名:张淑红  黄受方  陆鸣  郑媛媛
作者单位:首都医科大学附属北京友谊医院病理科,北京,100050
摘    要:目的探讨肾脏和肝脏血管平滑肌脂肪瘤(AML)、肺脏透明细胞"糖"瘤(CCST)、子宫血管周上皮样细胞肿瘤(PEComa)的共同病理学特征及共同的诊断和鉴别诊断要点。方法对肾脏和肝脏AML、肺脏CCST、子宫PEComa各1例的标本进行病理形态学和免疫组织化学观察。结果 4例不同部位和3种命名的肿瘤有相同的形态学,主要表现瘤细胞以上皮样细胞的组成,呈薄壁血管周围排列,免疫组化4例均HMB45阳性(4/4),3例SMA阳性(3/4)。结论上述发生在不同部位、不同命名的肿瘤,在形态和免疫组化上有共同特点:即血管周排列、瘤细胞呈上皮样;免疫组化表达黑色素标记物,亦可表达平滑肌标记物,这些特点支持统一为血管周上皮样细胞肿瘤(PEComas)的看法。

关 键 词:血管周上皮样细胞肿瘤  临床病理  免疫组织化学

Clinicopathological observation of neoplasms with perivascular epithelioid cell differention
ZHANG Shu-hong,HUANG Shou-fang,LU Ming,et al.. Clinicopathological observation of neoplasms with perivascular epithelioid cell differention[J]. Journal of Clinical and Experimental Medicine, 2011, 10(15): 1149-1152
Authors:ZHANG Shu-hong  HUANG Shou-fang  LU Ming  et al.
Affiliation:ZHANG Shu-hong,HUANG Shou-fang,LU Ming,et al.Department of pathololgy,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China.
Abstract:Objective To investigate the common pathological features,diagnosis,and differential diagnosis of angiomyolipoma(AML) of the kidney and liver,clear cell sugar tumor(CCST) of the lung,and perivascular epithelioid cell tumor(PEComa) of the uterus.Methods Each case of AML of the kidney and liver,CCST of the lung,and PEComa of the uterus was analyzed by light microscopy and immunohistochemistry.Results Four cases tumors of three different terms had the same morphology,mainly presented epithelioid neoplastic cel...
Keywords:PEComas  Clinical pathology  Immunohistochemistry  
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