| 肾细胞癌MN/CA9蛋白的表达及其生物学意义 |
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| 引用本文： | 贾绍昌,殷广福,苏长青,邓安梅,陈孙孝. 肾细胞癌MN/CA9蛋白的表达及其生物学意义[J]. 中华肿瘤防治杂志, 2000, 7(4): 375-376 |
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| 作者姓名： | 贾绍昌 殷广福 苏长青 邓安梅 陈孙孝 |
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| 作者单位： | 1. 解放军八一医院全军肿瘤研究中心,南京市,210002
2. 上海长征医院外科,上海市,200003 |
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| 摘 要： | 目的 :研究MN/CA9蛋白的表达和肾细胞癌的关系 ,探讨MN/CA9蛋白在肾细胞癌诊断研究中的应用。方法 :应用免疫组化和免疫印迹的方法 ,对正常肾组织、良性肾损害和肾细胞癌组织的MN/CA9蛋白的表达进行了分析。结果 :正常人肾组织和良性肾损害均为MN/CA9阴性 ,而在 30例肾癌中却有 2 8例为MN/CA9阳性 ,尤其是 2 6例富糖原型RCC均呈现MN/CA9强阳性。结论 :MN/CA9蛋白可作为肾细胞癌尤其是富糖原型肾细胞癌的一种标志物
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| 关 键 词： | 肾细胞癌 MN/CA9 |
| 修稿时间： | 2000-03-14 |
Expresion of MN/CA9 Protein in Renal Cell Carcinoma and its Significance |
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| JIA Shaochang,YIN Guangfu,SU Changqing,et al.. Expresion of MN/CA9 Protein in Renal Cell Carcinoma and its Significance[J]. Chinese Journal of Cancer Prevention and Treatment, 2000, 7(4): 375-376 |
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| Authors: | JIA Shaochang YIN Guangfu SU Changqing et al. |
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| Affiliation: | JIA Shaochang,YIN Guangfu,SU Changqing,et al.Cancer Center of PLA,Nanjing 81 Hospital,Nanjing 210002 |
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| Abstract: | Objective:To study the relationship between MN/CA9 protein expresion and renal cell carcinoma. Methods:Immunohistochemisty and immunoblotting were used to detect the expresion of renal cell carcinoma,normal renal tissue and benign renal lesion.Results:Expresion of MN/CA9 protein was found in renal cell carcinoma,especially in glycogenrich type of renal cell carcinoma,but negative in normal renal tissue and benign renal lesion.Conclusions:MN/CA9 may be a marker of glycogenrich type of renal cell caicinoma. |
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| Keywords: | renal cell carcinoma MN/CA9 protein |
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