The zoapatle III — Biological and uterotonic properties of aqueous plant extract |
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| Authors: | Héctor Ponce-Monter Hortensia Girón Xavier Lozoya Rául G. Enríquez Ezra Bejar Angel V. Estrada Alfredo J. Gallegos |
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| Affiliation: | 1. División de Biología Molecular, Unidad de Investigacíon Biomédica. Instituto Mexicano del Seguro Social (IMSS), México;2. Unidad de Investigación Biomédica en Medicina Tradicional y Herbolaria. Instituto Mexicano del Seguro Social (IMSS), México;3. Campo Agrícola Experimental, Valle de México. Instituto Nacional de Investigaciones Agrícolas, Secretaría de Agricultura y Recursos Hidráulicos de México (SARH) Mexico |
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| Abstract: | Differences in uterotonic activity were observed between zoapatle (Cerv.), plants growing in their natural habitat and plants growing in an experimental agricultural plot. Details of an analogic model for assaying uterotonic potency in guinea pig strips is described. Important species differences on the uterine response to zoapatle aqueous crude extract were noticed in rats, hamsters, guinea pigs, cats and Rhesus monkeys. The need for proper biological evaluation of chemical substances already isolated from zoapatle specimens, is mentioned, and the advantages of working with zoapatle specimens grown under controlled ecological conditions are pointed out. |
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