| 抗病毒药联合免疫增强剂治疗单疱病毒性角膜炎的临床与免疫学评价 |
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| 引用本文： | 张铭端,栾晓华,孟薇,赵喜珍.抗病毒药联合免疫增强剂治疗单疱病毒性角膜炎的临床与免疫学评价[J].眼科研究,1992(2). |
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| 作者姓名： | 张铭端 栾晓华 孟薇 赵喜珍 |
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| 作者单位： | 本溪钢铁公司总医院眼科 本溪117000
(张铭端，栾晓华，孟薇)，本溪钢铁公司总医院眼科 本溪117000(赵喜珍) |
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| 摘 要： | 用抗病毒药联合免疫增强剂对41例单疱病毒性角膜炎患者进行治疗。A 组患者(21例)用无环鸟苷、干扰素和转移因子治疗,B 组患者(20例)用无环鸟苷和干扰素治疗。结果A 组的复发率明显低于B组(P<0.05)。治愈后,A 组的淋巴细胞转化率(LTR)与E-玫瑰花结形成细胞(E-RFC)接近对照组水平(P>0.05),B 组的LTR 与E-RFC 则明显低于对照组与A 组水平(P<0.05)。提示转移因子能降低HSK 的复发率,并能提高HSK 患者的细胞免疫功能。
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| 关 键 词： | 单纯疱疹病毒性角膜炎 免疫疗法 免疫增强剂 |
Evaluation of Clinic and Immunology on Combination Therapy for Herpes Simplex Keratitis with Antiviral Drugs and Immunopotentialing Agent |
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| Zhang Mingduan,et al.Evaluation of Clinic and Immunology on Combination Therapy for Herpes Simplex Keratitis with Antiviral Drugs and Immunopotentialing Agent[J].Chinese Ophthalmic Research,1992(2). |
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| Authors: | Zhang Mingduan |
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| Institution: | Zhang Mingduan,et al Department of Ophthalmology,Worker's General Hospital,Benxi Steel Co.,Benxi |
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| Abstract: | 41 patients with herpes simplex keratitis (HSK) were treated with antiviral drugs andimmunopotentlaling agent.The patients of A group (21 cases) were treated with acyclovir,interferon and transfer factor and B group (20 cases) with acyclovir and interferon.Theresults showed that recurrent rate of A group was lower than that of B group (P<0.05).After recovery,lymphocytes trasformation rate (LTR) and E-rose formation cell (E-RFC)of A group came close to healthy controls (P>0.05).LTR and E-RFC of B group werelower than those of healthy controls and A group (P<0.05).These results suggested thattransfer factor could decrease recurrent rate of HSK and increase cellular immunefunction of the patients with HSK. |
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| Keywords: | herpes simplex keratitis immunotherapy immunopotentialing agent |
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