丁胺卡那、左氧氟沙星治疗耐多药肺结核临床观察

目的观察丁胺卡那，左氧氟沙星在耐多药肺结核（MDR-TB）治疗中的疗效。方法68例耐多药肺结核患者随机分为治疗组36例和对照组32例。治疗组采用3DZThVA／15DThV，对照组采用3DZThES／15DThE方案治疗。结果疗程结束后，治疗组痰菌阴转率，病灶吸收好转率分别为86．11％，88．39％，而对照组分别为59．38％，59．38％，两组比较，差异有显著性。结论对耐多药肺结核采用含丁胺卡那、左氧氟沙星的方案治疗MDR-TB效果肯定。

The clinical observation oil the effects of levofloxacin and amikacin oil the treatment of patients with multi-drug resistant pulmonary tuberculosis

Objective To observe the effects of levofloxacin and amikacin on multi-drug resistant pulmonary tuberculosis(MDR-TB).Methods 68 cases with MDR-TB were randomly divided into experimental group (n=36) and control group (n=32). Experimental group was treated with 3DZThVA/15DThV, control group was treated with 3DZThES/15DThE.Result When the course was completed, the sputum negative conversion rate and the radiographic resolution rate in the experimental group were 86.11%,88.36%,which were higher than the control 59.38% and 59.38%.Conclusion The treatment scheme of combine levofloxacin and amikacine was appropriate to apply on MDR-TB.