检测C反应蛋白在冠心病患者中的意义

目的探讨C反应蛋白（CRP）水平在冠心病中的变化及在预后判定中的意义。方法采用免疫透射比浊法测定CRP水平，其中稳定型心绞痛组28例，不稳定型心绞痛组29例，急性心肌梗死组23例和正常对照30例。结果CRP（mg／L）水平稳定型心绞痛组（5．35±3。82）与正常对照组（4．62±2．57）相比，有所升高，但无统计学意义（P〉0．05）；不稳定型心绞痛组（10．45±3．26）、急性心肌梗死组（14．67±5．81）显著高于稳定型心绞痛组和正常对照组，且二者相比，差异有统计学意义（P〈O．05和P〈0．01）。结论CRP是冠心病的独立危险因素，并可作为患者判断预后的指标。

Detection of C-reactive Protein in Patients with Coronary Heart Disease

[ Objective] To discuss the significance of level change of C-reactive protein （CRP） in prognosis of coronary heart dis- ease. [ Methods ] Immunity transmission turbidity was adopted to detect the CRP level, 28 patients were diagnosed stable angina, 29 were unstable angina, 23 were acute myocardial infarction, 30 were normal control patients. [ Results] CRP levels in stable angina group 15.32 ± 3.82 ） were higher than that of normal control group 14.62 ± 2.57 ）, but the difference was not significant （ P 〉 0.05 ） ; CRP levels in unstable angina group （ 10.45 ±3.26 ） and acute myocardial infarction （ 14.67 ± 5.81 ） were significantly high- er than that of stable angina group and normal control group（ P 〈 0.05 and P 〈 0.01）. [ Conclusion] CRP is an independent risk factor for CHD and can serve as indicators of prognosis in patients Key words C-reactive protein; Coronary heart disease