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深圳市某街道外来人口麻疹抗体水平监测分析及防制策略
引用本文:杨克志,马淑贞.深圳市某街道外来人口麻疹抗体水平监测分析及防制策略[J].职业与健康,2009,25(21):2296-2298.
作者姓名:杨克志  马淑贞
作者单位:1. 广东省深圳市龙岗区葵涌预防保健所,518119
2. 深圳市龙岗区龙岗预防保健所
摘    要:目的通过监测深圳市某街道辖区外来人口麻疹抗体水平,及时发现高危人群,为及时调整该辖区麻疹防制对策提供依据。方法将某街道外来人口分为8个年龄组,每组随机抽取不少于30人,共245人。采用酶联免疫吸附试验检测麻疹IgG抗体。检测结果采用Excel数据库分析处理。结果共监测合格标本245份,麻疹抗体阳性率75.51%,抗体几何平均滴度(GMT)为1:514,有效保护率57.14%。其中,1~10岁麻疹IgG抗体GMT均〉1:800,而10岁-抗体GMT均〈1:800,20岁一抗体有效保护率为37.50%,GMT也降到了1:351。所有年龄组中,0~8月龄抗体阳性率最低,有效保护率为0,GMT是1:115。同时对20名20-40岁育龄妇女的麻疹抗体滴度进行分析,阳性率为75.00%,有效保护率为35.00%,GMT为1:336。结论外来流动人口中青年劳务工及育龄妇女是麻疹减毒活疫苗(MV)强化免疫的重点人群。

关 键 词:麻疹  抗体水平监测  流动人口  预防接种

Monitoring of Measles Antibody Level on Migrant Populations in A Street of Shenzhen City
Institution:YANG Ke-zhi, MA Shu-zhen ( Kuiyong Institute of Health Inspection, Guangdong ,518119 , China )
Abstract: Objective ] To detect high-risk population of measles timely through monitoring the antibody levels of migrant population in a street of Shenzhen City, and provide evidence for timely adjusting measles control measures. Methods] The migrant population in the street were divided into 8 different age groups ( at least 30 people for each group, totally 245 people ). ELISA was adopted to determine the measles IgG antibody. The results were analyzed by Excel database. Results] Totally 245 qualified samples were tested, the measles antibody positive rate was 75.51%, the GMT was 1: 514.53, protection effective rate was 57.14%. Among which, GMT of measles IgG antibody of 1 - 10 years age group was 〉 1 : 800 ; that of 10 - 20 years age group was 〈 1 : 800 ; effective protection rate of 20 - 30 years age group was 37.50%, GMT decreased to 1: 351. Of all age groups, the infants less than 8 months had the lowest level of measles antibody, effective protection rate of this group was 0 and GMT was 1 : 115. Analysis of measles antibody titers on 20 women of childbearing age ( 20 - 40 years old) showed that the positive rate was 75 . 00%, effective protection rate was 35 . 00%, GMTwas 1:336. Conclusion] The focus population to inoculate measles vaccine among migrant population was the youth workers and childbearing aged women.
Keywords:Measles  Monitoring of antibody levels  Migrant population  Vaccination
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