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化疗相关性呃逆并文献分析
引用本文:何佳奇,韩一平,王辰飞.化疗相关性呃逆并文献分析[J].药学服务与研究,2009,9(3):191-193.
作者姓名:何佳奇  韩一平  王辰飞
作者单位:第二军医大学长海医院呼吸科,上海,200433
摘    要:部分中晚期肿瘤患者在联合化疗时会出现呃逆甚至顽固性呃逆,特别是在以铂类化合物和紫杉醇为基础化疗药物时,总的发生率约为0.39%。其中男性患者发生率明显高于女性患者。作者通过对大量文献进行检索分析后发现,化疗相关性呃逆的发生主要与化疗过程中应用地塞米松有关,同时其他化疗药物也有一定的作用。

关 键 词:呃逆  药物疗法,联合  地塞米松  药物副反应报告系统  综述

Literature analysis of chemotherapy-related hiccups
HE Jia-qi,HAN Yi-ping,WANG Chen-fei.Literature analysis of chemotherapy-related hiccups[J].Pharmaceutical Care and Research,2009,9(3):191-193.
Authors:HE Jia-qi  HAN Yi-ping  WANG Chen-fei
Institution:(Department of Respiratory Diseases,Changhai Hospital, Second Military Medical University,Shanghai 200433 ,China)
Abstract:Some patients with mid-advanced tumors may suffer from hiccups or even intractable hiccups in the course of combined chemotherapy,especially when platinum compounds or paclitaxel are applied as basic chemotherapeutics. In its approximately total morbidity of 0.39% ,the incidence in the male patients is significantly higher than that in the females. After analysis of many related literature at home and abroad, it is discovered that chemotherapy-related hiccups is related to application of dexamethasone. Meanwhile,the other chemotherapeutics should also have impact on it.
Keywords:hiccups  drug therapy  combination  dexamethasone  adverse drug reactions reporting system  reviews
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