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小鼠乳腺癌细胞系高肺转移亚系(Ca761-P93)的筛选及其生物学特性
引用本文:白莲花,钱振超.小鼠乳腺癌细胞系高肺转移亚系(Ca761-P93)的筛选及其生物学特性[J].大连医科大学学报,1995(3).
作者姓名:白莲花  钱振超
作者单位:Dept. of Pathophgsiology,Dalian Medical University
摘    要:本文在原有工作的基础上,对具有血道与淋巴道双向转移特性的小鼠乳腺癌Ca761-86细胞系进行了高转移潜能癌细胞亚系的筛选,使其自发肺转移率由未筛选时的20%稳定地提高到100%,定名为Ca761-P93,并对其生物学特性进行了研究,为肿瘤血道转移的实验研究提供了一个较好的高肺转移模型。

关 键 词:小鼠乳腺癌  高肺转移细胞系

The selection of high pulmonary metastatic substrain(Ca761-P93) from a murine mammary carcinoma cell line and its biological characteristics
Bai Lianhua, Qian Zhenchao.The selection of high pulmonary metastatic substrain(Ca761-P93) from a murine mammary carcinoma cell line and its biological characteristics[J].Journal of Dalian Medical University,1995(3).
Authors:Bai Lianhua  Qian Zhenchao
Abstract:Basing on previous work, we selected a high pulmonary metastatic substrain from a murine mammary carcinoma cell line(Ca761-86) which exibited metastatic characteristics both via blood and lymph ways. The results showed that the spontaneous pulmonary metastatic rate raised from 20% (non-selected Ca761-86) up to 100% (named as Ca761-P93).Mean while, we also studied its biological characteristics. Ca761-P93 provided a good high.pulmonary metastatic model for experimental cancer metastatic investigation.
Keywords:Murine mammary carcinoma  High pulmonary metastatic cell line
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