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In vitro activity of garenoxacin against recent clinical isolates of Chlamydia pneumoniae |
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| Authors: | Roblin Patricia M Reznik Tamara Hammerschlag Margaret R |
| Affiliation: | Division of Infectious Diseases, Department of Pediatrics, State University of New York Downstate Medical Center, Box 49, 450 Clarkson Avenue, Brooklyn, NY 11203-2098, USA |
| Abstract: | The in vitro activities of garenoxacin, a novel des-F (6)-quinolone, levofloxacin, moxifloxacin and clarithromycin were tested against 30 recent clinical isolates of Chlamydia pneumoniae. The minimal inhibitory concentration (MIC) at which 90% of the isolates were inhibited and the minimal bactericidal concentration (MBC) at which 90% of the isolates were killed by garenoxacin for C. pneumoniae was 0.03 mg/l (range 0.015–0.03 mg/l). |
| Keywords: | Chlamydia pneumoniae Garenoxacin MIC Fluoroquinolones |
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