| 鳞癌相关抗原监测肺鳞癌手术疗效的临床意义 |
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| 引用本文： | 曾亮,仇德惠,王群,徐正浪,郑如恒,陈可靖,顾伟光. 鳞癌相关抗原监测肺鳞癌手术疗效的临床意义[J]. 中国慢性病预防与控制, 1993, 0(6) |
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| 作者姓名： | 曾亮 仇德惠 王群 徐正浪 郑如恒 陈可靖 顾伟光 |
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| 作者单位： | 上海医科大学中山医院 200032(曾亮，仇德惠，王群，徐正浪，郑如恒，陈可靖)，上海医科大学中山医院 200032(顾伟光) |
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| 摘 要： | 用免疫放射量度分析法检测了48例肺鳞癌病人手术前后的血清鳞癌相关抗原(SCC Ag)水平.29例行根治性切除术,14例行姑息性切除术,5例行剖胸探查术.在根治性切除术后,异常升高的SCC Ag在72小时内降至正常水平,差异有显著意义(P<0.001).姑息性切除术后,SCC Ag常下降,仍高于正常值;剖胸探查术后,SCC Ag无明显改变.本研究证实SCC Ag对手术疗效反应敏感,是一种监测肺鳞癌病人手术疗效的很有价值的肿瘤标志物.
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| 关 键 词： | 鳞癌相关抗原 肺肿瘤 鳞形细胞癌 外科治疗 肿瘤标志物 |
CLINICAL EVALUATION OF SCC AG IN MONITORING SURGICAL THERAPEUTIC EFFECTS FOR SQUAMOUS CELL LUNG CANCER |
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| Zeng Liang,et at. CLINICAL EVALUATION OF SCC AG IN MONITORING SURGICAL THERAPEUTIC EFFECTS FOR SQUAMOUS CELL LUNG CANCER[J]. Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases, 1993, 0(6) |
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| Authors: | Zeng Liang et at |
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| Affiliation: | Zeng Liang,et atDepartment of Thoracic Surgery,Zhong Shan Hospital,Shanghai Medical University,Shanghai 200032 |
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| Abstract: | The serum lenels of squamous cell carcinoma associated antigen (SCC Ag) were measured prooperatively and postopera-tively by immunoradiometric assay in 48 patients with squamous cell lung carcinoma, of them 29 patients received curative resection, 14 patients palliative surgery, 5 patients exploratory thoracotomy- Elevated prooperative levels were found to drop dramatically to normal within 72 hours ,with significant difference (P<0. 001); In patients with palliative resection, the elevated levels declined but usually remained above the normal range; with exploratory thoracotomy, the levels showed little variation. The study proved that SCC Ag responded well to surgical therapeutic effects, it was considered to be a very useful tumor marker in monitoring surgical therapeutic effects for squamous cell iung carcinoma. |
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| Keywords: | Squamous cell carcinoma associated antigen (SCC Ag) Lung neoplasm Squamous cell carcinoma Surgical treatment Tumor marker |
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