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丹参水溶性成分提取工艺研究
引用本文:李向军,刘敏彦,赵兴茹,王玉峰,盖潇桦. 丹参水溶性成分提取工艺研究[J]. 中国中医药信息杂志, 2005, 12(12): 49-50
作者姓名:李向军  刘敏彦  赵兴茹  王玉峰  盖潇桦
作者单位:1. 河北以岭医药研究院有限公司,河北,石家庄,050035
2. 河北医科大学,河北,石家庄,050011
3. 石家庄以岭药业股份有限公司,河北,石家庄,050091
摘    要:目的优选丹参水溶性有效成分最佳提取工艺。方法采用正交试验法,以丹酚酸B、丹参素、原儿茶醛的含量为指标优选最佳提取工艺。结果丹参水溶性成分最佳提取工艺为A2B(3,2)C3,即加11倍量水提取2次,第1次2h,第2次1.5h。结论采用此方法省时、省工、节能,适合于大生产。

关 键 词:丹参  提取工艺  正交试验  丹酚酸B  丹参素  原儿茶醛
文章编号:1005-5304(2005)12-0049-02
收稿时间:2005-03-07
修稿时间:2005-03-07

Study On Extraction Method of Water-Soluble Active Principles of Salvia Miltiorrhiza
LI Xiang-jun,LIU Min-yan,ZHAO Xing-ru,et al. Study On Extraction Method of Water-Soluble Active Principles of Salvia Miltiorrhiza[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2005, 12(12): 49-50
Authors:LI Xiang-jun  LIU Min-yan  ZHAO Xing-ru  et al
Affiliation:1.Hebei lqling Academy of Medicine Limited Company, Shijiazhuang 050091, China; 2.Hebei University of Medicine, Shijiazhuang 050011, China
Abstract:Objective To study on the best extraction method of the water-soluble active principles of Salvia Miltiorrhiza matrine.Methods The extraction process was studied by orthogonal design with the content of Salvianolic Acid B,Danshensu and Protocatchuci aldehyde determined by RP-HPLC as index.Results A2B(3,2)C3 is the best extraction condition of aqueous part from Salvia Miltiorrhiza.That is to say,adding eleven-times water,heating two times,the first time last two hours and the second time last one and a half hours.Conclusion The extraction method for Salvia Miltiorrhiza can save time,working and energy and be suitable for the morden production.
Keywords:Salvia Miltiorrhiza  extraction process  orthogonal design  Salvianolic Acid B  Danshensu  Protocatchuci aldehyde
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