| 小剂量尿激酶、低分子肝素钙联合治疗不稳定型心绞痛的临床观察 |
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| 引用本文： | 孔印琢,张洪刚.小剂量尿激酶、低分子肝素钙联合治疗不稳定型心绞痛的临床观察[J].医学理论与实践,2007,20(1):11-13. |
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| 作者姓名： | 孔印琢 张洪刚 |
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| 作者单位： | 河南省安阳市第二人民医院心内科,455000 |
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| 摘 要： | 目的:观察小剂量尿激酶(UK)与低分子肝素钙联合治疗不稳定型心绞痛(UA)的临床疗效。方法:治疗组采用双盲、随机对照方法,UK剂量为0.5万U.kg-1.d-1于30min内静脉滴入,连续治疗5d,同时低分子肝素钙6150U皮下注射,12h一次,连用5d;对照组除不用UK外余治疗相同。观察心绞痛缓解程度、左室射血分数、心电图心肌缺血总负荷(TIB)、住院时间(HT)。结果:小剂量UK治疗组显效、总有效率优于对照组(P<0.05),TIB减少(P<0.01),HT缩短(P<0.01)。结论:小剂量UK与低分子肝素钙联合治疗UA临床效果显著,明显缩短住院时间。
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| 关 键 词： | 小剂量尿激酶 低分子肝素钙 不稳定型心绞痛 |
| 文章编号： | 1001-7585（2007）01-0011-03 |
| 收稿时间： | 2006-05-16 |
| 修稿时间： | 2006年5月16日 |
Clinical Observation of Therapeutic Effect of Low Dose of Urine Kinase Combined with Low Molecule Heparin Calcium for Unstable Angina Pectoris |
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| KONG Yinzhuo,ZHANG Honggang.Clinical Observation of Therapeutic Effect of Low Dose of Urine Kinase Combined with Low Molecule Heparin Calcium for Unstable Angina Pectoris[J].The Journal of Medical Theory and Practice,2007,20(1):11-13. |
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| Authors: | KONG Yinzhuo ZHANG Honggang |
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| Abstract: | Objective:To observe the effect of low dose of urine kinase combined with low molecule heparin calcium in treatment of unstable angina pectoris.Methods:In the treatment group the blind and random contrast method was used in this study.50000U·kg~(-1)·d~(-1) of UK was given by intravenous drip within 30min for 5 days.In the control group the treatment methods were same as in the treatment group but UK.The alleviation of angina pectoris,FVEF,TIB and HT were observed.Results: The excellent effective rate and total effective rate in treatment group were higher than that in control group(P<0.05),TIB was reduced(P<0.01) and HT was shortened(P<0.01).Conclusion:The low dose of UK combined with low molecule heparin calcium can obtain satisfactory therapeutic results of UA and shorten the HT. |
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| Keywords: | Low dose of urine kinase Low molecule heparin calcium Unstable angina pectoris |
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