Resistance to β-lactams among blood isolates of Salmonella spp. in European hospitals: results from the SENTRY Antimicrobial Surveillance Program 1997–98 |
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| Authors: | L S Tzouvelekis V Lukova P T Tassios A C Fluit R N Jones N J Legakis |
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| Institution: | Department of Microbiology, Medical School, University of Athens, Athens, Greece,;Eijkman-Winkler Institute, University Medical Center, Utrecht, The Netherlands and;Medical Microbiology Division, University of Iowa College of Medicine, Iowa City, USA |
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| Abstract: | The susceptibility to β -lactams and the β -lactamase content of 110 Salmonella spp. blood isolates collected during 1997–98 in 19 European centers participating in the SENTRY Surveillance Program were studied. Thirty-one isolates (28%) were resistant to penicillins, due to production of TEM-1 (27 isolates), OXA-1 (three isolates) or TEM-1 + OXA-1 (one isolate). All OXA-1 producers and 10 TEM-1-producing isolates were also resistant to penicillin–clavulanic acid combinations. In the latter isolates, this phenotype was associated with increased production of TEM-1. Sixteen TEM-1-producing Salmonella Enteritidis isolates and one OXA-1-producing S. Typhimurium isolate were able to transfer β -lactam resistance by conjugation. |
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| Keywords: | Salmonella β-lactams resistance |
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