限制性液体治疗对炎症性肠病术后并发症和预后的影响

目的:探讨限制性液体治疗对炎症性肠病(IBD)病人术后并发症和预后的影响. 方法:将87例IBD病人随机分为限制输液组(n=44)和标准输液组(n=43).限制输液组病人术后连续3d输注液体,20 ml/( kg·d),依据体重、碱缺失、血清乳酸水平、血氧合指标及其额外丢失量；标准输液组术后连续3d输注液体,按照生理需...

Effect of restrictive fluid therapy on postoperative complication in inflammatory bowel disease patients

Objective: To compare the outcome of restricted or standard intravenous fluid regimen in perioperative inflammatory bowel disease(IBD) patients.Methods: This study was designed as a prospective and randomized controlled trial.After informed consent was obtained,patients were allocated to either restricted or standard fluid regimen group.The primary end point was postoperative complications,including intestinal,liver,heart,respiratory,renal and clotting function,and the death rate,hospital stay and cost were also observed.Results: A total of 87 patients were assigned to restricted group(n=44) or standard group(n=43).The total fluid volume,total postoperative complications,incision infection,hospital stay and cost were significantly reduced in restricted group when compared with those in standard group.However,there were no significant differences on the incidence of heart failure,shock,lung infection,renal dysfunction and intestinal recover time between two groups.Conclusion: For IBD patients who undergo elective surgery,perioperative restrictive fluid management may be more beneficial,because it would reduce total postoperative complications and decrease hospital stay and expenses.