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血浆S-100B蛋白测定在外伤性颅内血肿诊疗中的临床意义
引用本文:胡殿雷,李伯安,王余军,韩松.血浆S-100B蛋白测定在外伤性颅内血肿诊疗中的临床意义[J].创伤外科杂志,2011,13(6):494-496.
作者姓名:胡殿雷  李伯安  王余军  韩松
作者单位:1. 徐州医学院附属第三医院神经外科,江苏,221003
2. 徐州医学院附属第三医院核医学科,江苏,221003
基金项目:江苏省徐州市科技局基金资助项目,获徐州市科技进步三等奖
摘    要:目的 探讨血浆S-100B蛋白在不同类型外伤性颅内血肿的诊断、分型、指导治疗中的临床价值.方法 颅内血肿116例,根据头颅CT分为硬膜外血肿(52例)、硬膜下血肿(32例)、脑内血肿(32例)三组,伤后早期(6小时内)抽取血浆测定S-100B蛋白含量,伤后每24小时送检1次,动态测定(3~7天).三组两两比较.结果 脑...

关 键 词:颅内血肿  S-100B蛋白  预后

Clinical significance of serum S-100B protein in diagnosing and treating traumatic intracranial haematoma
Institution:HU Dian-lei,LI Bo-an,WANG Yu-jun,et al. (Department of Neurosurgery,3rd Hospital Affiliated to Xuzhou Medical College,Xuzhou 221003,China)
Abstract:Objective To investigate the value of S-100B protein as a biology marker in diagnosing,classifying and treating traumatic intracranial haematoma.Methods Totally 116 cases of traumatic intracranial haematoma were included in this study,and divided into three groups including epidural hematoma group(52 cases),subdural hematoma group(32 cases),intracerebral hematoma group(32 cases) based on head CT.Venous blood samples for S-100B protein were obtained as soon as possible after admission and every 24 hours during the 3-7 days after injury.Three groups were compared with each other.Results Patients with intracerebral hematoma had significantly higher serum S-100B values compared with other groups,and the serum S-100B value in the subdural hematoma group was different with that in the epidural hematoma group.Conclusion S-100B protein has reliable value in the diagnosis and prognosis of traumatic intracranial haematoma.
Keywords:intracranial haematoma  S-100B protein  prognosis
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