| 抗精神病药对QTc间期的影响 |
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| 引用本文： | 王晓朵,陈月敏,颜文伟.抗精神病药对QTc间期的影响[J].上海精神医学,2002,14(1):43-44. |
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| 作者姓名： | 王晓朵 陈月敏 颜文伟 |
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| 作者单位： | 1. 200051,长宁区精神卫生中心
2. 上海市精神卫生中心 |
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| 摘 要： | 目的探讨研究抗精神病药对心脏的安全性.方法对服用单一抗精神病药治疗的精神分裂症病人检测心电图(ECG),观察比较其QTc间期.结果服奥氮平患者QTc间期延长的百分比显著低于服其他典型与非典型抗精神病药患者.结论在治疗精神分裂症及相关疾病时,只有奥氮平最少可能出现导致恶性心律异常的QTc间期延长.
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| 关 键 词： | 抗精神病药 心电图 QTc |
Cardiological safety of antipsychotics |
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| Wang Xiaoduo,Chen Yuemin,Yan Wenwei.Cardiological safety of antipsychotics[J].Shanghai Archives of Psychiatry,2002,14(1):43-44. |
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| Authors: | Wang Xiaoduo Chen Yuemin Yan Wenwei |
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| Abstract: | Objectives: To investigate the cardiological safety of antipsychotics. Methods: To observe the ECG records of the schizophrenic patients who take only one kind of antipsychotics, and measure QTc. Results: The percents of patients whose QTc exceeded the normal limit were calculated, and that of olanzapine was the least one, only 3% (1/33). Conclusion: Olanzapine is the one which would not induce abnormal QTc elongation. |
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| Keywords: | Antisychotics ECG QTc |
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