肥胖及血脂异常与2型糖尿病关系

目的 探讨肥胖及血脂异常与2型糖尿病的关系.方法 采用病例对照研究方法,选取重庆市3所医院的糖尿病门诊和住院初诊患者及其他疾病和门诊健康体检者396例作为调查对象;其中糖尿病病例组184例,对照组212人.对调查对象进行问卷调查、体格检查和生化指标等实验室检测.结果 病例组体质指数(BMI)、腰臀比(WHR)、血清总胆固醇(TC)、甘油三酯(TG)均高于对照组,差异均有统计学意义(P<0.05);病例组超重及肥胖检出率(64.67%)、腹型肥胖检出率(77.17%)、高TC检出率(27.17%)、高TG检出率(50.00%)均高于对照组(45.28%,64.15%,14.15%,35.38%),差异均有统计学意义;经多因素非条件Logistic回归分析显示,高胆固醇、超重及肥胖是糖尿病的主要危险因素.结论 肥胖和血脂异常与2型糖尿病相关,控制体重、合理膳食是预防2型糖尿病发生的重要措施.

Relationship between obesity, dyslipidemia and type 2 diabetes

Objective To study the relationship between obesity,dyslipidemia and type 2 diabetes.Methods Acase control study among 184 type 2 diabetes patients from 3 hospitals and 212 normal health examinees was conducted in Chongqing city during the period of Oct,2008 to Feb,2009.Results The body mass index(BMI),waisthip ratio(WHR),serum total cholesterol(TC),and triglyce ride(TG) of the case group were higher than those of the control group And the test demonstrated that the differences were statistically significant.The over weight and obesity rates(64.67%),the detection rates of high TC(27.17%) and high TG(50.00%) of the case group were higher than those of the control group with significant differences.The multifactor non conditional logistic regression analysis showed that hypercho lesterolemia,overweight and obesity were major risk factors for type 2 diabetes.Conclusion Obesity and dyslipidemia are related to the occurrence of type 2 diabetes.Controlling weight and a reasonable diet are important measures to preventtype 2 diabetes.