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Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria |
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| Authors: | Chengjung Lai Natalie Pursell Jessica Gierut Utsav Saxena Wei Zhou Michael Dills Rohan Diwanji Chaitali Dutta Martin Koser Naim Nazef Rachel Storr Boyoung Kim Cristina Martin-Higueras Eduardo Salido Weimin Wang Marc Abrams Henryk Dudek Bob D. Brown |
| Affiliation: | 1. Dicerna Pharmaceuticals, Inc., Cambridge, MA 02140, USA;2. Hospital Universitario de Canarias, Centre for Biomedical Research on Rare Diseases (CIBERER), Universidad La Laguna, Tenerife, Spain |
| Abstract: |  |
| Keywords: | primary hyperoxaluria lactate dehydrogenase glycolate oxidase calcium oxalate kidney stones end-stage renal disease RNAi small interfering RNAs |
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