Comparison of MR and PET imaging for the evaluation of liver metastases |
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Authors: | Yang Ming Martin Diego R Karabulut Nevzat Frick Mathis P |
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Affiliation: | Department of Radiology, West Virginia University, School of Medicine, Morgantown, West Virginia 26505-9235, USA. |
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Abstract: | PURPOSE: To compare the accuracy of fluoro-18-deoxyglucose positron emission tomography (FDG-PET) and dynamic-enhanced magnetic resonance imaging (MRI) scans in the diagnosis of liver metastatic lesions from colon and other sources. MATERIALS AND METHODS: Thirty consecutive patients with known or suspected metastatic lesions were scanned by both MRI and PET. Histopathology and/or clinical outcome, including cross-sectional imaging follow up, were used as a gold standard. RESULTS: Of 30 patients, 16 were positive by pathology and/or clinical outcome and 14 were negative for liver metastases. The sensitivity, specificity, and positive and negative predictive values on MRI were 85.7%, 100%, 100%, and 89%, respectively, compared to 71%, 93.7%, 90.9%, and 79% on FDG-PET. The difference between the two methods was not significant (X(2) = 0.2, P > 0.05). CONCLUSION: Our study showed no significant difference in detection of liver metastases using MRI or FDG-PET. However, MRI has advantages in spatial resolution and lesion characterization. |
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Keywords: | MRI FDG‐PET liver lesions metastatic malignancy |
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