Osteoclastoma of the nasopharynx

Osteoclastoma involves the long bones of the extremities and some of the flat bones such as the sacrum, mandible patella and vertebrae. Eggston and Wolff (1947) mentioned the possibility of its origin from bones of the upper jaw, ethmoid and sphenoid sinuses. Amongst the skull bones, Rosenwasser (1969) described a case of giant cell tumour of the middle ear, yet such a tumour arising from the nasopharynx and sphenoid seems to be extremely rare. A rare case of osteoclastoma of the nasopharynx with extensive local invasion, multiple cranial nerve involvement and fatal termination is described. The differential diagnosis and histological features have been discussed.