晶状体核硬化及其影响因素的研究进展

晶状体核硬化是白内障的表现之一,晶状体核在眼内受多种因素的影响发生硬化混浊。研究发现随着年龄的增大、核混浊、核颜色加深核硬度增加;在晶状体的老化过程中,游离水含量增加,而结合水含量下降,脱水使晶状体相应的干重增加以及非水溶性蛋白向核中心逐渐增加。玻璃体切除术后晶状体的微环境改变,从而加速核硬化的进展。晶状体核硬化混浊还受环境、饮食及代谢等多种因素影响。

The lens nuclear sclerosis and associated factors

The lens nuclear sclerosis is one of cataract manifestations. The nucleus of crystalline lens may become sclerosis and opacities under influences of numerous factors in eyes. The hardness of the lens nucleus can increase with aging, opacity and dark color. With aging process of the lens, the amount of free water in the nucleus increases, and otherwise the composed water gets less. This dehydration increases the lens dry weight and the water-insoluble proteins gradually approach to the center of the nucleus. The nuclear sclerosis accelerates after vitrectomy mainly due to the changes of micro-environment around the lens. The nuclear sclerosis and opacities are also associated with environment, diet, metabolism and many other factors.