脑梗死后痴呆的危险因素分析

目的探讨脑梗死后痴呆的发生率及其危险因素。方法选择200例脑梗死患者,入院时均详细询问病史、进行血生化检查、神经功能缺损评分及智能评估。结果200例脑梗死患者中有65例发生痴呆(痴呆组),发生率为32.50%;135例无痴呆发生(非痴呆组)。高龄、文化程度低、无职业、家庭支持不足、有卒中史、自理能力差者其痴呆组显著高于非痴呆组(P<0.05,P<0.01);发生脑梗死后肌酐及血糖、纤维蛋白原、总胆固醇、甘油三酯痴呆组显著高于非痴呆组(P<0.05,P<0.01)、脂蛋白水平两组差异无显著性意义(P>0.05);脑梗死发生于左半球高,右半球低;脑梗死多发于体积大、神经功能缺损程度严重者,其痴呆组显著高于非痴呆组(均P<0.01)。结论脑梗死后痴呆常见,且与年龄、文化程度、职业、家庭支持不足、有卒中足、脑梗死的部位、体积、病灶数目和神经功能缺损的程度、血糖、纤维蛋白原、血脂及肌酐水平升高等因素有关。

Current Status of Cleaning and Disinfection Equipment and Their Management in Supply Rooms in the Hospitals in Guangdong Province

Objective To study the incidence of and risk factors for dementia after the cerebral infarction. Methods Two hundred cases of cerebral infarction were selected. At admission, the medical history was asked in detail, blood biochemical test was carried out, the damage of nerve system MMSE was evaluated three months after cerebral infarction and the intelligent assessment was performed. Results Among the 200 cases of cerebral infarction, dementia occurred in 65 cases (32.5 %). Senility, low educational level, no occupation, insufficient family support, stroke history and bad life ability were the factors for the occurrence of dementia following the cerebral infarction. After cerebral infarction, creatine, blood glucose, fibrinogen and triglyceride in dementia group were significantly higher than in non-dementia group (P<0.05, P<0.01), but there was no significant difference in the lipoprotein between two groups (P>0.05). The incidence of cerebral infarction in left sphere was lower than in right sphere. Multiple cerebral infarction and large size and severe damage of nerve system MMSE were related with the occurrence of dementia following the cerebral infarction (P<0.01). Conclusion Dementia often occurs after cerebral infarction. It is related with following factors: age, educational level, occupation, insufficient family support, stroke history, the site and size of cerebral infarction, the focus number, the damage of nerve system, blood glucose, fibrinogen, lipoprotein, triglyceride and creatine etc.