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Treatment of pulmonary hypertension with riociguat: a review of current evidence and future perspectives
Authors:Afroditi K. Boutou  Georgia Pitsiou
Affiliation:1. Department of Respiratory Medicine, G. Papanikolaou Hospital , Thessaloniki, Greece afboutou@yahoo.com;3. Department of Respiratory Failure, Aristotle University of Thessaloniki , Thessaloniki, Greece
Abstract:ABSTRACT

Introduction

Pulmonary arterial hypertension (PAH) is still a chronic disorder characterized by high morbidity and mortality. Chronic thromboembolic pulmonary hypertension (CTEPH) is another form of pulmonary hypertension (PH) for which pulmonary endarterectomy (PEA) is the treatment of choice. However, not all patients are operable, while PH is often recurrent or persistent. Thus, for both disorders novel treatment options are urgently needed.
Keywords:Riociguat  pulmonary arterial hypertension  chronic thromboembolic pulmonary hypertension  monotherapy  combination treatment
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