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Outcome factors in surgically treated patients for cervical spondylotic myelopathy
Authors:Jiolanda Zika  Sotirios Giannopoulos  Ioannis Kastanioudakis  Athanasios P. Kyritsis  Spyridon Voulgaris
Affiliation:1. Department of Rehabilitation Medicine, University Hospital of Ioannina, Ioannina, Greece;2. Department of Neurology, University Hospital of Ioannina, Ioannina, Greece"ORCIDhttps://orcid.org/0000-0001-7443-5179;3. Department of Otolaryngology Head and Neck Surgery, University Hospital of Ioannina, Ioannina, Greece;4. Department of Neurology, University Hospital of Ioannina, Ioannina, Greece;5. Department of Neurosurgery, University Hospital of Ioannina, Ioannina, Greece
Abstract:Context/Objective: To investigate prospectively preoperative parameters that might be related to the outcome of surgically treated patients for cervical spondylotic myelopathy (CSM).

Design: Prospective study.

Setting: Single Center in Ioannina, Greece.

Participants: Thirty-six patients were included in the study. There were 21 males and 15 females, mean age 50.8 years, range 39–70 years. The mean BMI was 27.3.

Outcome measures: From each patient, we recorded age, sex, BMI, symptoms, duration of symptoms, comorbidities, lifestyle, myelopathy grade based on MRI and levels of compression. All patients completed the modified JOA (mJOA) and NPE questionnaires preoperatively and at 1, 3, 12 months and 5-years postoperatively.

Results: The mean mJOA score significant improved from 10.8?±?1.9 points preoperatively to 16.6?±?2.2 points at 12 months postoperatively. The mean mJOA score at 5-years postoperatively was 15.5?±?3 points. The difference was still highly significant. The mean NPE score significant improved from 59.8?±?12.2 points preoperatively to 28.2?±?8.5 points at 1 month, to 35.8?±?8.1 points at 3 month and to 28.2?±?8.8 points at 12 months postoperatively. Younger patients had significant higher baseline mJOA scores and significant higher mJOA scores 5-year postoperatively. No correlation was found between sex, BMI, symptom duration, baseline mJOA or myelopathy grade and outcome at 12 months or 5-year postoperatively.

Conclusion: Age was highly predictive factor of outcome for patients undergoing surgical treatment of CSM.
Keywords:Cervical spondylotic myelopathy  Surgery  outcome  ACDF
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