| 一种兔脑血管痉挛模型的建立 |
| |
| 引用本文： | 柏鲁宁,周雄波,赵晓平,郭强,范小璇.一种兔脑血管痉挛模型的建立[J].汕头大学医学院学报,2008,21(4). |
| |
| 作者姓名： | 柏鲁宁 周雄波 赵晓平 郭强 范小璇 |
| |
| 作者单位： | 陕西中医学院附属医院神经外一科,陕西,咸阳,712000 |
| |
| 摘 要： | 目的:建立一种结果可靠而制作简单的蛛网膜下隙出血(SAH)后脑血管痉挛(CVS)动物模型。方法:实验动物分为对照组与模型组,采用枕大池2次注血法建立CVS动物模型,通过尸体解剖和脑血管造影观察基底动脉(BA)痉挛。结果:尸体解剖模型组BA周围和枕大池内均有血凝块;造影发现模型组中day3、5组与对照组比有统计学意义(P<0.05)。结论:枕大池2次注血法是建立CVS动物模型的一种可靠方法。
|
| 关 键 词： | 蛛网膜下隙出血 脑血管痉挛 动物模型 |
An Experimental Model of Cerebral Vasospasm in Rabbits |
| |
| BAI Lu-ning,ZHOU Xiong-bo,ZHAO Xiao-ping,GUO Qiang,FAN Xiao-xuan.An Experimental Model of Cerebral Vasospasm in Rabbits[J].Journal of Shantou University Medical College,2008,21(4). |
| |
| Authors: | BAI Lu-ning ZHOU Xiong-bo ZHAO Xiao-ping GUO Qiang FAN Xiao-xuan |
| |
| Abstract: | Objective:To establish a simple and reliable model of cerebral vasospasm(CVS).Method:The subjects were randomly divided into control group and CVS group."Two-hemorrhage" method was used to establish the rabbit model.By the autopsy and the cerebral angiography,the CVS of basilar artery(BA)was observed.Results:In the CVS group,the blood clot could be seen around BA and in cisterna magna.Compared with the control group,the calibre of BA in the day3 and day5 groups became thin(P<0.05).Conclusion: "Two-hemorrhage" is a simple and reliable method for establishing model of CVS in rabbits. |
| |
| Keywords: | subarachnoid hemorrhage cerebral vasospasm animal model |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
