17例纤维板层型肝癌临床分析

目的：探讨纤维板层型肝癌的发病特点、临床症状、实验室检查、影像表现、病理特征、治疗方法及生存时间。方法：结合近年文献,回顾性分析17例确诊为纤维板层型肝癌患者的临床资料。结果：发现17例患者9例为中青年人（年龄在45岁以下）占58.8%,其临床表现和体征不明显,实验室检查基本正常,影像表现为单个结节,手术切除率高,3年和5年生存率分别达到76.5%和58.5%。结论：纤维板层型肝癌主要病理特点为纤维板层基质和强嗜酸性颗粒,好发于青年人,症状轻,与乙型肝炎无正相关联,临床进展慢,预后好。

Clinical analysis of 17 cases of fibrolamellar hepatocarcinoma

Objective：To investigate the clinical features,laboratory test results,imaging findings,pathological characteristics,treatment and survival time of the fibrolamellar hepatocarcinoma.Methods：To analyze the clinical data of 17 patients diagnosed as fibrolamellar hepatocarcinoma.Results：Among the 17 patients with fibrolamellar hepatocarcinoma,9 patients were under 45 years old.The fibrolamellar hepatocarcinoma has no obvious clinical manifestations and signs,with approximate normal laboratory test results,showed only a single nodule in image,it was relatively easy removed by surgery,and the survival time of 3 years and 5 years were 76.5% and 58.5%.Conclusion：The fibrolamellar hepatocarcinoma was common in young person,its characteristic pathological feature was with lamellar fiber matrix and strong eosinophilic granular,with mild clinical symptoms,had no obvious relationship with HBV,with relatively slow clinical progression,and good prognosis.