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外源性纤维粘连蛋白对即刻再植牙愈合影响的实验
引用本文:张旭光,张震康.外源性纤维粘连蛋白对即刻再植牙愈合影响的实验[J].中华口腔医学杂志,1996,31(1):16-18.
作者姓名:张旭光  张震康
作者单位:北京医科大学口腔医学院
摘    要:为研究外源性纤维粘连蛋白对再植牙愈合的影响,作者选用2只成年猕猴,拔除上中切牙,实验组牙用0.5mg/ml的纤维粘连蛋白溶液处理,以其同名牙作为对照。牙齿即刻原位再植,术后4周、8周时分别切取标本,行普通光学显微镜形态学观察和图像处理分析。结果显示:纤维粘连蛋白的应用不仅可以明显促进再植牙牙周纤维的再附着、降低牙根吸收率,而且可以明显减轻愈合过程中的炎症反应。

关 键 词:再植牙  纤维粘连蛋白  牙周再附着  牙根吸收

Experimentalstudyonthehealingofimmediatereplantedtoothafterusingexogenousfibronectin
ZhangXuguang,ZhangZhenkang,GengWenqi,et al..Experimentalstudyonthehealingofimmediatereplantedtoothafterusingexogenousfibronectin[J].Chinese Journal of Stomatology,1996,31(1):16-18.
Authors:ZhangXuguang  ZhangZhenkang  GengWenqi  
Institution:ZhangXuguang,ZhangZhenkang,GengWenqi,etal.SchoolofStomatology,BeijingMedicalU-niversity,Beijing100081
Abstract:Thepurposeofthisarticleistostudytheefectonthehealingofimmediatereplantedtethafterthebiologicalcharactersofrootswerechangedbyusingexogenousfibronectin(Fn).Twoadultrhesusmonkeyswerechosenintheexperiment.Upperincisorsofeachmonkeywereextracted.Theteethofexperimentalgroupwereextractedtherootstreatedby0.5mg/mlFnsolutionandre-plantedimmediately.Therootsofanotheranimalwereusedascontrols.Afteroperations,theexper-imentalspecimensof4weeksand8weekswereexamedhistologicalybylightmicroscopeandstudiedquantitativelybycomputerimageanalysissystem.TheresultsrevealthatFncanenhanceperiodontalhealingbyimprovingperiodontalreatachmentandreducingrootresorptionofreplantedtooth.Fnhasalsothefunctiontoreduceinflammatoryreactionssignificantlyduringthehealingprocess.
Keywords:ReplantationoftoothFibronectinHealingofreplantedtoothRootre-sorption  
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