| 补肾调冲方与脱氢表雄酮治疗卵巢储备功能降低所致不孕症临床疗效观察 |
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| 引用本文： | 夏天,赵丽颖,王宝娟,付于,马瑞红. 补肾调冲方与脱氢表雄酮治疗卵巢储备功能降低所致不孕症临床疗效观察[J]. 天津中医药大学学报, 2014, 33(2): 71-74 |
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| 作者姓名： | 夏天 赵丽颖 王宝娟 付于 马瑞红 |
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| 作者单位： | 天津中医药大学第一附属医院, 中西医结合生殖疾病协同创新中心, 天津 300193;天津中医药大学, 天津 300193;天津中医药大学第一附属医院, 中西医结合生殖疾病协同创新中心, 天津 300193;天津中医药大学第一附属医院, 中西医结合生殖疾病协同创新中心, 天津 300193;天津中医药大学第一附属医院, 中西医结合生殖疾病协同创新中心, 天津 300193 |
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| 基金项目： | 国家自然科学基金（81273791）。 |
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| 摘 要： | [目的]观察补肾调冲方与脱氢表雄酮(DHEA)治疗卵巢储备功能降低(DOR)所致不孕症患者的临床疗效。[方法]将60例DOR所致不孕症的患者随机分为3组,即补肾调冲方组、DHEA组、安慰剂组,均治疗3个月经周期。[结果]补肾调冲方可显著改善DOR患者临床症状、血清性激素水平及四清抗苗勒氏管激素(AMH)、抑制素B(INHB)值,增加卵巢窦卵泡数(AFC),提高卵巢储备功能,其疗效优于DHEA,差异有统计学意义(P0.05)。[结论]补肾调冲方在治疗因DOR所导致不孕症方面较DHEA疗效显著,且未发现有明显的毒副作用和不良反应,值得临床推广应用。
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| 关 键 词： | 不孕症 卵巢储备功能降低 补肾调冲方 脱氢表雄酮 |
| 收稿时间： | 2013-12-27 |
Effect of Bushen Tiaochong recipe and dehydroepiandrosterone for infertility women with diminished ovarian reserve |
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| XIA Tian,ZHAO L-ying,WANG Ba-juan,FU Yu and MA Ru-hong. Effect of Bushen Tiaochong recipe and dehydroepiandrosterone for infertility women with diminished ovarian reserve[J]. Journal of Tianjin University of Traditonal Chinese Medicine, 2014, 33(2): 71-74 |
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| Authors: | XIA Tian ZHAO L-ying WANG Ba-juan FU Yu MA Ru-hong |
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| Affiliation: | Collaborative Innovation Center of Reproductive Disease with Combination of TCM and Western Medicine, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Collaborative Innovation Center of Reproductive Disease with Combination of TCM and Western Medicine, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Collaborative Innovation Center of Reproductive Disease with Combination of TCM and Western Medicine, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Collaborative Innovation Center of Reproductive Disease with Combination of TCM and Western Medicine, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| Abstract: | [Objective] To evaluate the effect of Bushen Tiaochong recipe(BTR) and dehydroepiandrosterone(DHEA) for infertility women with diminished ovarian reserve. [Methods] Sixty infertility women caused by DORassigned into 3 groups randomized, interventions of which were BTR, DHEA, and placebo respectively. All enrolled women would be treated for 3 menstrual cycles. [Results] Women's clinical symptoms, serum hormone level, serum AMH and INHB concentration and AFC number were all improved in BTR and DHEA groups, but former was even better than latter. [Conclusion] The effect of BTR for infertility women with DOR is more remarkable than DHEA, and BTR is safer, which should be apply in clinical practice. |
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| Keywords: | infertility diminished ovarian reserve Bushen Tiaochong recipe dehydroepiandrosterone |
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