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Shift in phenotype of acute T-lymphocytic leukemia to eosinophilic leukemia: a case report |
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| Authors: | P P Preis C C Zielinski W Linkesch P Bettelheim T Radaskiewicz M Pavelka O Haas P Aiginger |
| Affiliation: | 2nd Department of Medicine, Vienna University Hospital. |
| Abstract: | Acute T-lymphocytic leukemia diagnosed in a 14-year old boy on the basis of typical cell morphology, as well as by membrane antigen analysis with monoclonal antibodies, shifted to the phenotype of an acute eosinophilic leukemia 5 months after the initiation of chemotherapy. The transformation was evident by a change in morphology of cells derived from bone marrow aspirates, by cytochemistry and by a shift in the membrane antigen pattern. |
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