| 维生素E抑制3T3-L1前脂肪细胞的分化 |
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| 引用本文： | 郑奕迎,刘声远,马兰,龙儒桃. 维生素E抑制3T3-L1前脂肪细胞的分化[J]. 海南医学院学报, 2010, 16(9): 1117-1119 |
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| 作者姓名： | 郑奕迎 刘声远 马兰 龙儒桃 |
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| 作者单位： | 1. 海南医学院病理生理学教研室,海南,海口,571101
2. 华中科技大学同济医学院病理生理学系,湖北,武汉,430030 |
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| 摘 要： | 目的:研究维生素E对3T3-L1前脂肪细胞增殖和分化的影响。方法:利用MTT研究维生素E对3T3-L1前脂肪细胞增殖的影响,利用油红O染色法测定维生素E对3T3-L1前脂肪细胞分化的影响。结果:维生素E对3T3-L1前脂肪细胞增殖无影响,10～100μmol/L维生素E能抑制3T3-L1前脂肪细胞的分化。结论:维生素E对前脂肪细胞分化具有抑制作用。
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| 关 键 词： | 维生素E 碘 3T3-L1 增殖 分化 肥胖 MTT 油红O染色法 |
Inhibitory effect of vitamin E on differentiation of 3T3-L1 preadipocyte |
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| ZHENG Yi-ying,LIU Sheng-yuan,MA Lan,LONG Ru-tao. Inhibitory effect of vitamin E on differentiation of 3T3-L1 preadipocyte[J]. Journal of Hainan Medical College, 2010, 16(9): 1117-1119 |
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| Authors: | ZHENG Yi-ying LIU Sheng-yuan MA Lan LONG Ru-tao |
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| Affiliation: | 1.Department of Phathology and Physiology,Hainan Medical University,Haikou 571101;2.Faculty of Phathology and Physiology,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China) |
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| Abstract: | Objective：To study the effects of vitamin E on proliferation and differentiation of 3T3-L1 preadipocyte.Methods：The effect of vitamin E on the proliferation of 3T3-L1 was determined by MTT.Oil red O staining was used to determine the differentiation rate and level of 3T3-L1 preadipocytes.Results：Vitamin E inhibited the differentiation of preadipocytes at 10 μmol/L and 100 μmol/L.Conclusions：Vitamin E could inhibit the differentiation of 3T3-L1 preadipocyte. |
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| Keywords: | 3T3-L1 MTT |
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