| 长春花内生真菌的分离及其发酵产生药用成分的初步研究 |
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| 引用本文： | 张玲琪,郭波,李海燕,曾松荣,邵华谷苏,魏蓉城.长春花内生真菌的分离及其发酵产生药用成分的初步研究[J].中草药,2000,31(11):805-807. |
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| 作者姓名： | 张玲琪 郭波 李海燕 曾松荣 邵华谷苏 魏蓉城 |
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| 作者单位： | 云南大学生物系(昆明 650091);云南大学生物系(昆明 650091);云南大学生物系(昆明 650091);云南大学生物系(昆明 650091);云南省微生物研究所;云南省微生物研究所 |
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| 基金项目： | 国家自然科学基金资助项目(No39860005);云南省应用基础研究基金资助项目(No96C009M) |
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| 摘 要： | 首次报道从长春花 Catharanthus roseus (L.) G. Don茎的韧皮部中分离出尖孢镰刀菌Fusariumoxysporum, 为该植物的一种内生真菌, 并用 TLC和 HPLC对该菌的97CG3菌株培养物进行了分析, 初步结果表明该真菌能产生抗癌药长春新碱成分。
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| 关 键 词： | 长春花 内生真菌 尖孢镰刀菌 长春新碱 |
| 收稿时间： | 1999/12/18 0:00:00 |
Preliminary Study on the Isolation of Endophytic Fungus of Catharanthus roseus and Its Fermentation to Produce Products of Therapeutic Value |
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| Zhang Lingqi,Guo Bo,Li Haiyan,Zeng Songrong,Shao Hua and Gu Su.Preliminary Study on the Isolation of Endophytic Fungus of Catharanthus roseus and Its Fermentation to Produce Products of Therapeutic Value[J].Chinese Traditional and Herbal Drugs,2000,31(11):805-807. |
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| Authors: | Zhang Lingqi Guo Bo Li Haiyan Zeng Songrong Shao Hua and Gu Su |
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| Institution: | Department of Biology, Yunnan University (Kunming 650091);Department of Biology, Yunnan University (Kunming 650091);Department of Biology, Yunnan University (Kunming 650091);Department of Biology, Yunnan University (Kunming 650091);Yunnan Institute of Microbiology;Yunnan Institute of Microbiology |
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| Abstract: | An endophytic fungus, Fusarium oxysparum, (97CG3) was isolated from the phloem (inner bark) of Catharanthus roseus (L. ) G Don for the first time Metabolic products of cultured 97CG3 have been analysed by TLC and HPLC It was shown that the fungus can produce vincristine which has an anticancer activity. |
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| Keywords: | Catharanthus roseus (L ) G Don endophytic fung us Fusarium oxysporumvincri stine |
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