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Translocation t(8;16)(p11;p13) in neonatal acute monocytic leukaemia |
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| Authors: | T. Hanada I. Ono Y. Minosaki N. Moriyama S. Nakahara A. Ohtsu |
| Affiliation: | (1) Department of Paediatrics, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tennodai, 305 Tsukuba-shi, Ibaraki-ken, Japan;(2) Department of Paediatrics, Kensei Hospital, 309-12 Iwase-machi, Ibaraki-ken, Japan;(3) Department of Dermatology, Kensei Hospital, 309-12 Iwase-machi, Ibaraki-ken, Japan |
| Abstract: | A recent report demonstrated that t(8;16) (p11;p13) may be linked to acute monocytic leukaemia (AMoL) of differentiated subtype (M5b) with active haemophagocytosis by leukaemic cells. Only two cases of neonatal AMoL with t(8;16)(p11;p13) have been reported; M5b with haemophogocytosis and M5a. We report a case of neonatal AMoL (M5b) with t(8;16)(p11;p13), but haemophagocytosis by the leukaemic cells was not detected. |
| Keywords: | Acute monocytic leukaemia Haemophagocytosis t(8:16)(p11:p13) |
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