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超声造影联合血清CA125检测在卵巢肿块良恶性鉴别诊断中的初步应用
引用本文:彭梅,张新书,姜凡,张学珍. 超声造影联合血清CA125检测在卵巢肿块良恶性鉴别诊断中的初步应用[J]. 上海医学, 2011, 34(2)
作者姓名:彭梅  张新书  姜凡  张学珍
作者单位:1. 安徽医科大学第二附属医院超声诊断科,合肥,231601
2. 蚌埠医学院第一附属医院超声科
基金项目:安徽省卫生厅临床医学应用技术项目资助
摘    要:目的探讨超声造影联合血清CA125检测在卵巢肿块良恶性鉴别诊断中的应用价值.方法回顾性分析49个卵巢肿块的彩色多普勒、超声造影表现以及血清CA125检测水平,并与临床诊断结果进行对照.结果 49个卵巢肿块中,彩色多普勒超声检查判断肿块良恶性的准确率、敏感度和特异度分别为67.35%(33/49)、70.00%和63.16%,超声造影检查判断卵巢肿块良恶性的准确率、敏感度和特异度分别为85.71%(42/49)、86.67%和84.21%,超声造影检查联合血清CA125检测判断卵巢肿块良恶性的准确率、敏感度和特异度分别为97.96%(48/49)、100.00%和94.74%.3种检查方法的诊断准确率、敏感度和特异度的差异均有统计学意义(P值均<0.05).结论超声造影检查能显示卵巢肿块内微小血管的血流灌注和血管形态,超声造影检查结合血清CA125检测能进一步提高对卵巢肿块良恶性的鉴别诊断价值.

关 键 词:卵巢肿块  超声检查  造影剂  血清CA125

Contrast-enhanced ultrasonography combined with detection of serum CA125 in differentiating malignant and benign ovarian masses
PENG Mei,ZHANG Xinshu,JIANG Fan,ZHANG Xuezheng. Contrast-enhanced ultrasonography combined with detection of serum CA125 in differentiating malignant and benign ovarian masses[J]. Shanghai Medical Journal, 2011, 34(2)
Authors:PENG Mei  ZHANG Xinshu  JIANG Fan  ZHANG Xuezheng
Affiliation:PENG Mei,ZHANG Xinshu,JIANG Fan,ZHANG Xuezheng Department of Ultrasound Diagnosis,The Second Affiliated Hospital of Anhui Medical University,Hefei 231601,China
Abstract:Objective To evaluate the value of contrast-enhanced ultrasonography(CEUS)combined with detection of serum CA125 in the differential diagnosis of benign and malignant ovarian tumors.Methods The findings of color Doppler,CEUS and serum CA125 levels of 49 ovarian masses were retrospectively analyzed,and the results were compared with those of clinical diagnoses.Results The diagnostic accuracy,sensitivity and specificity of the color Doppler were 67.35%,70.00% and 63.16%,respectively;those of the contrast-enha...
Keywords:Ovarian masses  Ultrasonography  Contrast media  Serum CA125  
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