Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration |
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| Authors: | Margherita Galletti,Silvia Cantoni,Filippo Zambelli,Sabrina Valente,Massimiliano Palazzini,Alessandra Manes,Gianandrea Pasquinelli,Antonello Mai,Nazzareno Galiè ,Carlo Ventura |
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| Affiliation: | 1. National Institute of Biostructures and Biosystems (NIBB), University of Bologna, Bologna, Italy;2. Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy;3. Società Italiana Studi Medicina della Riproduzione (S.I.S.Me.R.), Reproductive Medicine Unit, Bologna, Italy;4. Department of Drug Chemistry & Technologies, Sapienza University of Rome, Rome, Italy;5. Stem Wave Institute for Tissue Healing (SWITH), Gruppo Villa Maria (GVM) and Ettore Sansavini Health Foundation – ONLUS, Lugo, Ravenna, Italy |
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| Abstract: | Pulmonary Arterial Hypertension (PAH) is a rare and devasting condition characterized by elevated pulmonary vascular resistance and pulmonary artery pressure leading to right-heart failure and premature death. |
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| Keywords: | Pulmonary hypertension Histone deacetylase Proliferation Migration Smooth muscle cells |
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