Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin |
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Authors: | Karin V Greco,Giovanna Nalesso,Magdalena K Kaneva,Joanna Sherwood,Asif J IqbalNiloufar Moradi-Bidhendi,Francesco Dell&rsquo AccioMauro Perretti |
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Affiliation: | The William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, United Kingdom |
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Abstract: | |
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Keywords: | AB, Alcian Blue ADAMT, A Disintegrin And Metalloproteinase with Trombospondin motif AHAC, adult human articular chondrocyte BAX, Bcl-2-associated X protein BCL-2, B-cell leukemia-lymphoma-2 protein BMP2, Bone Morphogenic Protein type 2 CT, Calcitonin CTR, calcitonin receptor CREB, cAMP response element-binding protein ECM, extracellular matrix EGFP, enhanced green fluorescent protein FSK, forskolin GAG, glycosaminoglycan GPCR, G-protein coupled receptor MMP, matrix metalloproteinase NFAT, nuclear factor of the activated T-cells OA, Osteoarthritis PG, prostaglandin PKA, protein kinase A PLC, Phospholipase C PRED, prednisolone RA, Rheumatoid Arthritis TUNEL, Terminal deoxynucleotidyl transferase dUTP nick end labeling. |
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