内放疗支架治疗食管癌的临床应用

目的探讨内放疗支架(即125Ⅰ粒子支架)治疗中晚期食管癌的可行性及疗效。方法选择15例中晚期食管癌患者,在X线监视下经口置入捆绑125Ⅰ放射粒子的食管支架到病变部位。结果术后全部病例吞咽困难等临床症状明显改善,未出现感染,食管穿孔、大出血、放射性肺炎等严重并发症。随访3～6个月复查示14例病变体积较前不同程度缩小,1例病变增大且组织长入支架上口,发生再狭窄。结论食管内放疗支架临床应用疗效显著,且安全可行。

The clinical application of intra-radiation stenting for the treatment of esophageal carcinoma

Objective To discuss the feasibility and curative effect of intra-radiation stenting(125Iparticle stent)for the treatment of advanced esophageal cancers.Methods Fifteen patients with advanced esophageal cancer were enrolled in this study.Under X-ray guidance the esophageal stent,which was tied up with 125I radioactive particles,was orally inserted to the diseased region of the esophagus.The clinical manifestations and imaging findings were observed and the results were analyzed.Results After the operation all the clinical symptoms such as dysphasia showed an obvious improvement.No serious complications such as infection,hemorrhage,radiation pneumonia,etc.Occurred.The re-examination at 3-6 months after the treatment showed that the tumor size Was decreased in a certain degree in 14 patients,and in the remaining one patient the lesion became bigger and grew to the upper opening of the stent,resulting in esophageal restenosis.Conclusion The intra-esophageal implantation of radioactive stent is a feasible and safe treatment for the advanced esophageal cancers with excellent curative results.