周围型肝内胆管细胞癌的动态MR成像研究

目的 评价周围型肝内胆管细胞癌（PCC）的动态MRI所见。方法 17例PCC病人造影后，早期、中期和晚期行动态MRI。评价项目包括肿瘤的增强形式及其与病理特征的关系、肿瘤周围的楔形增强区、肝内胆管的扩张、血管受累及肿瘤的肝外浸润征象。结果 早期的边缘部增强并伴随着造影时间推移的向心性增强是最常见的造影所见形式（9例）。在17例病人中，10例可见到肿瘤周围的楔形增强区，11例可见胆管扩张，8例可见血管受累，2例可见肝外浸润。结论 增强形式与病理特征（细胞和纤维化的数量及分布）有关。早期的边缘部增强并伴随着造影时间推移的向心性增强可认为是PCC相对常见的特征。

Dynamic MR imaging of intrahepatic peripheral cholangiocarcinoma

Objective To evaluate the dynamic MR imaging findings of peripheral cholangiocarcinoma (PCC) of the liver. Methods Seventeen patients with PCC underwent dynamic MRI during the early, middle, and delayed phase after contrast medium administration. Enhancement pattern of the tumor, the wedge-like enhancement area peripheral to the tumor, dilatation of the intrahepatic biliary ducts, vascular involvement, and extrahepatic tumor invasion were evaluated. Results Early peripheral enhancement with progressive and concentric filling by contrast medium was the most frequent enhancement pattern (9 patients). A wedge-like enhancement area was observed in 10 patients. Ductal dilatation was found in 11 patients. Vascular involvement and extrahepatic invasion were seen in 8 and 2 patients, respectively. Conclusion Enhancement pattern is relative to the character of pathology (quantity and distribution of cell and fibrosis). Early peripheral enhancement with progressive and concentric filling by contrast medium may be specific for PCC.