Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer |
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| Authors: | Mokrane Yacoub Serge Milin Jacques Irani Ga?lle Fromont |
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| Affiliation: | 1. Mayo Clinic Department of Urology, Rochester, MN;2. Mayo Clinic Department of Pathology, Rochester, MN;3. Mayo Clinic Department of Health Sciences Research, Rochester, MN;2. Paris South Medical University, Le Kremlin Bicêtre, France;3. Institut Langevin, ESPCI Paris, PSL Research University CNRS UMR 7587, INSERM ERL U-979, Paris, France;4. Imagerie par Résonance Magnétique Médicale et Multi-Modalités, CNRS UMR8081, Université Paris Sud, CEA Service Hospitalier Frédéric Joliot, Orsay Cedex, France;5. Supersonic Imagine, Aix en Provence Cedex, France;11. Department of Adult Radiology, Necker University Hospital, Paris, France;12. Paris Descartes University, Paris, France |
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| Abstract: | Mesonephric remnant (MR) hyperplasia in the prostate is a rarely reported condition that is usually distinguished from prostatic adenocarcinoma by the absence of cytologic atypia as well as the absence of prostatic markers (prostate-specific antigen and prostatic acid phosphatase) expression. We report a case of prostatic MR hyperplasia with architectural and cytologic atypia in a 56-year-old man. The microscopic appearance strongly suggested malignancy, but immunohistochemistry allowed the diagnosis to be corrected. The presence of MRs in prostate tissues may be more common than appreciated or reported. Once the possibility is considered, the diagnosis is easily confirmed using immunochemistry. |
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