Determination of Urinary Trace Elements (Arsenic,Copper, Cadmium,Manganese, Lead,Zinc, Selenium) in Patients with Blackfoot Disease |
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| Authors: | Jin-Lian Tsai Pin-Hua Horng Tzung-Jeng Hwang John W Hsu Ching-Jyi Horng |
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| Institution: | 1. Graduate Institute of Occupational Safety College of Health Science Kaohsiung Medical University , Kaohsiung, Taiwan;2. Faculty of Medicinal and Applied Chemistry , College of Life Science Kaohsiung Medical University , Kaohsiung, Taiwan;3. Graduate Institute of Pharmaceutical Sciences College of Pharmacy Kaohsiung Medical University , Kaohsiung, Taiwan;4. Institute of Preventive Medicine College of Public Health National Taiwan University , Taipei, Taiwan;5. School of Medicine Kaohsiung Medical University , Kaohsiung, Taiwan;6. Faculty of Medicinal and Applied Chemistry College of Life Science Kaohsiung Medical University , Kaohsiung, Taiwan |
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| Abstract: | To determine the relationship of arsenic, copper, cadmium, manganese, lead, zinc and selenium to Blackfoot disease (BFD, a peripheral vascular disorder endemic to areas of Taiwan, which has been linked to arsenic in drinking water) the authors measured the amount of these substances in urine from BFD patients, using atomic absorption spectrometry. Results indicate significantly higher amounts of urinary arsenic, copper, cadmium, manganese, and lead for BFD patients than for normal controls, also significantly lower urinary zinc and selenium. |
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| Keywords: | atomic absorption spectrometry Blackfoot disease trace elements urine analysis |
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